Grey's Anatomy: see how the actors changed over time

Grey's Anatomy
Ellen Pompeo - then
Ellen Pompeo - now
Patrick Dempsey - then
Patrick Dempsey - now
Justin Chambers - then
Justin Chambers - now
Sara Ramirez - then
Sara Ramirez - now
Katherine Heigl - then
Katherine Heigl - now
Sandra Oh - then
Sandra Oh - now
Chandra Wilson - then
Chandra Wilson - now
Jessica Capshaw - then
Jessica Capshaw - now
Kevin McKidd - then
Kevin McKidd - now
Camilla Luddington - then
Camilla Luddington - now
Jesse Williams - then
Jesse Williams - now
Sarah Drew - then
Sarah Drew - now
Caterina Scorsone - then
Caterina Scorsone - now
James Pickens Jr. - then
James Pickens Jr. - now
Jason Winston George - then
Jason George - now
Kelly McCreary - then
Kelly McCreary - now
Grey's Anatomy

Nearly two decades ago, one of the most successful series of recent television began: 'Grey's Anatomy.' Over time, some protagonists left the series, while others stayed and evolved. See in this gallery how everyone changed over time and where they went.

Ellen Pompeo - then

Who doesn't love Meredith Grey? She is the narrator and main character of the series. Everything has always evolved around her. The actress, Ellen Pompeo, was 35 years old when the series started. She had an angelic face.

Ellen Pompeo - now

Of course, the years pass for everyone, but beauty has not abandoned the actress, even after so many hours as a busy doctor!

Patrick Dempsey - then

At the age of 39, Patrick Dempsey began playing the unforgettable Dr. Shepherd. He was a regular face in the series until the 11th season, released in 2014.

Patrick Dempsey - now

After leaving Grey's Anatomy, the actor appeared in other productions, such as 'Bridget Jones' Baby' and the series 'Devils' (2020). He also made a comeback in the 17th season of 'Grey's Anatomy'!

Justin Chambers - then

Justin Chambers is Alex Karev in the award-winning series. At 34 years of age, he managed to perfectly embody this role of a misunderstood, rebellious boy in the first season.

Justin Chambers - now

Alex Karev proved to be an extraordinary paediatric surgeon, to the extent that we cannot imagine the series without the actor anymore. He is now in his 50s.

Sara Ramirez - then

Dr. Torres was the most competent traumatologist at Seattle Grace Hospital. She was also the protagonist of the most interesting romances. Sara Ramirez, responsible for playing the role, left us in 2016 after recording season 12.

Sara Ramirez - now

After a season out of the spotlight, Sara Ramirez appeared in the CBS drama series 'Madam Secretary.' She is in her 40s now.

Katherine Heigl - then

Katherine Heigl played Izzi Stevens, a generous and passionate resident from the same class as Meredith Grey. She was 36 when the series began.

Katherine Heigl - now

In 2010, she abandoned her role in the series and focused on other projects. Among the most recent is the series 'Suits' in 2018 and 2019, where she played Samantha Wheeler.

Sandra Oh - then

Dr. Yang has been  missed since she decided to take a new career path after ten seasons. Sandra Oh successfully played her role and was almost as important as Ellen Pompeo in the series.

Sandra Oh - now

Starting in 2018, fans of the actress could admire her as the lead in the series 'Killing Eve,' for which she won a Golden Globe for Best Actress. The funny and exciting spy series lasted for four highly entertaining seasons.

Chandra Wilson - then

The actress rose to fame thanks to her character, Miranda Bailey, a demanding doctor who goes to great lengths to save lives.

Chandra Wilson - now

Chandra Wilson is still part of the cast of Grey's Anatomy to this day. The job got her four Emmy nominations for Best Supporting Actress already.

Jessica Capshaw - then

Before she was Dr. Arizona Robbins in Grey's Anatomy, Jessica Capshaw appeared in the film 'Minority Report,' released in 2002 and directed by Steven Spielberg.

Jessica Capshaw - now

The actress left the series in 2018 after nine years. In 2020, she starred in the Netflix-produced comedy 'Holidate' and in 2022 we could see her in the film 'Dear Zoe.'

Kevin McKidd - then

Dr. Owen Hunt arrived in the fifth season of the series and was responsible for bringing fame to this actor, who had previously appeared in films such as 'Hannibal Rising' / 'Kingdom of Heaven'.

Kevin McKidd - now

Nearly in his 50s, the actor is still very attached to his role in 'Grey's Anatomy,' and he even got to direct some episodes.

Camilla Luddington - then

Jo Wilson appeared in the ninth season of the series as one of the most promising residents. In 2011, Camilla Luddington also played Kate Middleton in the film 'William & Kate.'

Camilla Luddington - now

Now in her late 30s, she has seen her career flourish since she became one of the main characters in 'Grey's Anatomy.'

Jesse Williams - then

Jackson Avery brought fresh air to the hospital where so many stories took place. The actor who plays him joined in the sixth season of the series, where he remains to date.

Jesse Williams - now

In parallel to Grey's Anatomy, Williams has worked on other productions, such as the miniseries 'Little Fires Everywhere' with Kerry Washington and Reese Witherspoon, and a recent Netflix rom-com, 'Your Place or Mine' (2023). He seems to have changed little over time.

Sarah Drew - then

Sarah Drew joined the series in 2009 in the role of the sensitive Dr. April Kepner.

Sarah Drew - now

The actress stepped down from her role in 2018. Her latest TV work includes the teen series 'Cruel Summer' on Freeform and 'Amber Brown' on Apple TV Plus.

Caterina Scorsone - then

Amelie Shepper is the sister of Dereck Shepper. The Canadian-American actress Caterina Scorsone has been in the permanent cast of the series since 2014.

Caterina Scorsone - now

In 2020, Caterina Scorsone played the same role in 'Station 19,' a series inspired by 'Grey's Anatomy' but set in a fire station.

James Pickens Jr. - then

Richard Webber is the leader of the group, the voice of experience that advises doctors, nurses, and residents. This has been his role ever since the series began.

James Pickens Jr. - now

James Pickens Jr. never abandoned 'Grey's Anatomy.' We could see how he matured during all the seasons.

Jason Winston George - then

In 2010, George joined 'Grey's Anatomy' as Ben Warren. Together with Dr. Bailey he had a beautiful love story.

Jason George - now

The actor is still in the cast, although the number of his scenes has decreased. From 2013 to 2016, he was in the cast of 'Mistresses,' and he has appeared in 'Station 19' since 2018.

Kelly McCreary - then

Dr. Maggie Pierce appeared in TV's most famous hospital in 2014. She was one of the protagonists who took the series in a different direction after several seasons had passed.

Kelly McCreary - now

Her character also appears in the series 'Station 19', but the main role of McCreary's career is that of 'Grey's Anatomy.'